Pre-trial results
APTAGENIC™ TREATMENT IN SWINE
Infectious Pathogen: vPRRS
Dosing Differential: Aptagenic™ and No Treatment
Study Overview and Process
- Sixteen pigs were divided into four subgroups (1, 2, 3, and 4) of four each.
- On Day Zero, all sixteen pigs were injected with equal levels of Porcine Reproductive and Respiratory Syndrome (vPRRS) strain LHVA-93-3 which was then active in Eastern Canada.
- Group 1 was left untreated.
- Pigs in the remaining three groups each received one dose of Aptagenic™ A-505 (deemed most effective of 10 prototype Aptagenics™ produced for the study on a staggered timetable:
- Group 2 was treated on day zero about 12 hours after infection.
- Group 3 was treated on day one.
- Group 4 was treated on Day two.
Study Results
1. Untreated pigs lost a significant amount of weight and needed to be culled.
2. All of the treated pigs survived the infection and thrived after recovery.
3. Positive results were achieved using only 500 picograms of Aptagenic™ therapeutic per kilogram of animal weight (considered minimal dosage).
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